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Vijay Pande on betting small after a16z's $4B biotech fund

Vijay Pande discusses his new AI-native fund VZVC and the shift in biology from discovery to engineering.

By TMRO Staff·1 min read
Vijay Pande on betting small after a16z's $4B biotech fund
TMRO Report

Key points

  • Pande left a16z's ~$4B biotech practice last year.
  • He now runs VZVC, a much smaller, AI-native fund.
  • He says biology is shifting from discovery to engineering.
  • Clinical trials remain brutally expensive.
  • He advocates for open, shared datasets over walled-off ones.

What happened

Vijay Pande, who left a16z's roughly $4 billion biotech practice last year, has started a new, much smaller AI-native fund called VZVC. In a recent interview, he discussed why biology is finally shifting from a "discovery" science to an "engineering" one, why clinical trials are still brutally expensive, and why he thinks open, shared datasets (not walled-off ones) are what will actually let AI transform medicine.

Pande emphasized that his new approach involves betting smaller, saying, "We're not doing 30 bets a year." This contrasts with the larger scale of his previous role at a16z.

Why it matters

Pande's shift from a large fund to a smaller one reflects a broader trend in biotech investing, and his views on open datasets could influence how AI is applied to medicine.

Sources

TMRO Report writes original coverage based on the material listed above.